Laboratory for Fetal and Regenerative Biology: Publications

Selected Publications:

1. Silk Fibroin-Based Therapeutics for Impaired Wound Healing. Lehmann T, Vaughn AE, Seal S, Liechty KW, Zgheib C. Pharmaceutics. 2022 Mar 16;14(3):651. doi: 10.3390/pharmaceutics14030651. PMID: 35336024 Free PMC article. Review.

2. Discovery of Small Molecule Activators of Chemokine Receptor CXCR4 That Improve Diabetic Wound Healing. Xu J, Hu J, Idlett-Ali S, Zhang L, Caples K, Peddibhotla S, Reeves M, Zgheib C, Malany S, Liechty KW. Int J Mol Sci. 2022 Feb 16;23(4):2196. doi: 10.3390/ijms23042196. PMID: 35216311 Free PMC article.

3. Lung function improves after delayed treatment with CNP-miR146a following acute lung injury. Niemiec SM, Hilton SA, Wallbank A, Louiselle AE, Elajaili H, Hu J, Singh S, Seal S, Nozik E, Smith B, Zgheib C, Liechty KW. Nanomedicine. 2022 Feb;40:102498. doi: 10.1016/j.nano.2021.102498. Epub 2021 Nov 26. PMID: 34838994 Free PMC article.

4. Cerium oxide nanoparticle conjugation to microRNA-146a mechanism of correction for impaired diabetic wound healing. Dewberry LC, Niemiec SM, Hilton SA, Louiselle AE, Singh S, Sakthivel TS, Hu J, Seal S, Liechty KW, Zgheib C. Nanomedicine. 2022 Feb;40:102483. doi: 10.1016/j.nano.2021.102483. Epub 2021 Nov 6. PMID: 34748956

5. Photopolymerized Zwitterionic Hydrogels with a Sustained Delivery of Cerium Oxide Nanoparticle-miR146a Conjugate Accelerate Diabetic Wound Healing. Stager MA, Bardill J, Raichart A, Osmond M, Niemiec S, Zgheib C, Seal S, Liechty KW, Krebs MD. ACS Appl Bio Mater. 2022 Mar 21;5(3):1092-1103. doi: 10.1021/acsabm.1c01155. Epub 2022 Feb 15. PMID: 35167263

6. Evaluation of skin care concerns and patient's perception of the effect of NanoSilk Cream on facial skin. Louiselle AE, Niemiec S, Azeltine M, Mundra L, French B, Zgheib C, Liechty KW. J Cosmet Dermatol. 2022 Mar;21(3):1075-1085. doi: 10.1111/jocd.14198. Epub 2021 May 10. PMID: 33934488

7. Topical gel-based biomaterials for the treatment of diabetic foot ulcers. Bardill JR, Laughter MR, Stager M, Liechty KW, Krebs MD, Zgheib C. Acta Biomater. 2022 Jan 15;138:73-91. doi: 10.1016/j.actbio.2021.10.045. Epub 2021 Oct 30. PMID: 34728428 Review.

8. Cerium oxide nanoparticle delivery of microRNA-146a for local treatment of acute lung injury. Niemiec SM, Hilton SA, Wallbank A, Azeltine M, Louiselle AE, Elajaili H, Allawzi A, Xu J, Mattson C, Dewberry LC, Hu J, Singh S, Sakthivel TS, Sea S, Nozik-Grayck E, Smith B, Zgheib C, Liechty KW. Nanomedicine. 2021 Jun;34:102388. doi: 10.1016/j.nano.2021.102388. Epub 2021 Mar 20. PMID: 33753282 Free PMC article.

9. Role of microRNAs in Pressure Ulcer Immune Response, Pathogenesis, and Treatment. Niemiec SM, Louiselle AE, Liechty KW, Zgheib C. Int J Mol Sci. 2020 Dec 23;22(1):64. doi: 10.3390/ijms22010064. PMID: 33374656 Free PMC article. Review.

10. Nanosilk Increases the Strength of Diabetic Skin and Delivers CNP-miR146a to Improve Wound Healing. Niemiec SM, Louiselle AE, Hilton SA, Dewberry LC, Zhang L, Azeltine M, Xu J, Singh S, Sakthivel TS, Seal S, Liechty KW, Zgheib C. Front Immunol. 2020 Oct 30;11:590285. doi: 10.3389/fimmu.2020.590285. eCollection 2020. PMID: 33193424 Free PMC article.

11. Silk fibroin nanofibrous mats for visible sensing of oxidative stress in cutaneous wounds. Singh S , Cortes G , Kumar U , Sakthivel TS , Niemiec SM , Louiselle AE , Azeltine-Bannerman M , Zgheib C , Liechty KW , Seal S. Biomater Sci. 2020 Nov 7;8(21):5900-5910. doi: 10.1039/d0bm01325k. Epub 2020 Sep 25. PMID: 32975269

12. A Large Mammalian Model of Myocardial Regeneration After Myocardial Infarction in Fetal Sheep. Hodges MM, Zgheib C, Liechty KW. Adv Wound Care (New Rochelle). 2021 Apr;10(4):174-190. doi: 10.1089/wound.2018.0894. Epub 2020 Jul 7. PMID: 32496979 Free PMC article.

13. Mesenchymal stromal cells contract collagen more efficiently than dermal fibroblasts: Implications for cytotherapy. Hilton SA, Dewberry LC, Hodges MM, Hu J, Xu J, Liechty KW, Zgheib C. PLoS One. 2019 Jul 15;14(7):e0218536. doi: 10.1371/journal.pone.0218536. eCollection 2019. PMID: 31306414 Free PMC article.

14. Injectable, self-healable zwitterionic cryogels with sustained microRNA - cerium oxide nanoparticle release promote accelerated wound healing. Sener G, Hilton SA, Osmond MJ, Zgheib C, Newsom JP, Dewberry L, Singh S, Sakthivel TS, Seal S, Liechty KW, Krebs MD. Acta Biomater. 2020 Jan 1;101:262-272. doi: 10.1016/j.actbio.2019.11.014. Epub 2019 Nov 11. PMID: 31726250

15. Use of Cerium Oxide Nanoparticles Conjugated with MicroRNA-146a to Correct the Diabetic Wound Healing Impairment. Zgheib C, Hilton SA, Dewberry LC, Hodges MM, Ghatak S, Xu J, Singh S, Roy S, Sen CK, Seal S, Liechty KW. J Am Coll Surg. 2019 Jan;228(1):107-115. doi: 10.1016/j.jamcollsurg.2018.09.017. Epub 2018 Oct 22. PMID: 30359833 Free PMC article.

Find a full list of Laboratory for Fetal and Regenerative Biology publications at PubMED.