Matthew B. Gretzer, MD, FACS

Associate Professor, Clinical Surgery
Director, Genitourinary Reconstructive Surgery

Matthew B. Gretzer, MD, FACS

Associate Professor, Clinical Surgery
Director, Genitourinary Reconstructive Surgery

Matthew Gretzer, MD, is an associate clinical professor of surgery and the director of genitourinary reconstructive surgery at the University of Arizona Department of Surgery, College of Medicine - Tucson. Dr. Gretzer specializes in the management of urethral stricture disease and is one of only a few Arizona urologists that routinely performs a high volume of complex urethral reconstruction (urethroplasty) cases. In addition, he has advanced urologic training in all aspects of genitourinary reconstruction and prosthetics and performs numerous penile implant and artificial urinary sphincter cases, both initial and revisional as referred from other urologists. The highly complex nature of these procedures improves the quality of life for these patients following cancer therapy and traumatic injury. 

Since joining the University of Arizona Division of Urology faculty in 2005, Dr. Gretzer has established the Division of Urology as a center of excellence in genitourinary reconstruction. When he arrived, there were no other urethral reconstruction specialists in Arizona. He has since worked hard to develop a wide referral network that spans all of Arizona as well as all of its neighboring states. As this program has matured in Arizona, patients are now routinely referred to the University of Arizona in Tucson for this unique management of their treatment instead of being referred out of state.

"I treat everyone as I would want to be treated and strive to maintain accessibility, communication, and above" - Matthew Gretzer, MD, FACS.

Research Interests: 

New therapy for male incontinence
Urethral stricture management outcomes
Genitourinary trauma management
Voiding fluid dynamics

  • MD: University of Texas Health Science Center - San Antonio, 1998
Honors and Awards
  • Arizona Representative to the Western Section American Urological Association
  • President of the Arizona Urological Society
  • Johns Hopkins Hospital/School of Medicine, General Surgery Resident, 2000
  • Johns Hopkins Hospital/School of Medicine, James Buchanan Brady Urological Institute, Urology, 2004
  • Johns Hopkins Hospital, General Surgery, 1999
  • Johns Hopkins Hospital, James Buchanan Brady Urological Institute, Advanced Urological Training, 2004-2005
Board Certifications
  • American Board of Urology, Diplomate
  • Fellow American College of Surgeons

Select Publications


Dyer, A., P. M. Sadow, E. Bracamonte, and M. Gretzer, "Immunoglobulin G4-related Retroperitoneal Fibrosis of the Pelvis.", Rev Urol, vol. 16, issue 2, pp. 92-4, 2014. PMCID: PMC4080856  PMID: 25009451


Nguyen, M. M., F. R. Ahmann, R. B. Nagle, C-H. Hsu, J. A. Tangrea, H. L. Parnes, M. H. Sokoloff, M. B. Gretzer, and H-H. Sherry Chow, "Randomized, double-blind, placebo-controlled trial of polyphenon E in prostate cancer patients before prostatectomy: evaluation of potential chemopreventive activities.", Cancer Prev Res (Phila), vol. 5, issue 2, pp. 290-8, 2012 Feb. PMCID: PMC3273617  PMID: 22044694


Sroka, I. C., T. A. Anderson, K. M. McDaniel, R. B. Nagle, M. B. Gretzer, and A. E. Cress, "The laminin binding integrin alpha6beta1 in prostate cancer perineural invasion.", J Cell Physiol, vol. 224, issue 2, pp. 283-8, 2010 Aug. PMCID: PMC4816210  PMID: 20432448


Malik, G., E. Rojahn, M. D. Ward, M. B. Gretzer, A. W. Partin, J. O Semmes, and R. W. Veltri, "SELDI protein profiling of dunning R-3327 derived cell lines: identification of molecular markers of prostate cancer progression.", Prostate, vol. 67, issue 14, pp. 1565-75, 2007 Oct 01. PMID: 17705230


Gretzer, M. B., and A. W. Partin, "Advances in prostate cancer treatment: highlights from the 2nd international prostate cancer congress, st. Thomas, u.s. Virgin islands, july 17-20, 2002.", Rev Urol, vol. 5, issue 2, pp. 111-7, 2003 Spring. PMCID: PMC1473003  PMID: 16985627